2. Signaling Pathways
  3. GPCR/G Protein
    Neuronal Signaling
  4. 5-HT Receptor
  5. 5-HT Receptor Isoform
  6. 5-HT Receptor Modulator

5-HT Receptor Modulator

5-HT Receptor Modulators (16):

Cat. No. Product Name Effect Purity
  • HY-12723
    Apomorphine
    		Modulator 99.48%
    Apomorphine is an orally active agonist of Dopamine receptor. Apomorphine can be used in study Parkinson, biphasic dyskinesias, urinary dysfunction,,dystonia, dyspnoea, anismus and belching.
  • HY-14539S2
    Clozapine-d4
    		Modulator 99.82%
    Clozapine-d4 is the deuterium labeled Clozapine. Clozapine is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors.
  • HY-14539S
    Clozapine-d8
    		Modulator 99.68%
    Clozapine-d8 is the deuterium labeled Clozapine. Clozapine is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors.
  • HY-B2089
    Cinitapride
    		Modulator 98.24%
    Cinitapride is a nonselective 5-HT1 and 5-HT4 receptors agonist and a 5-HT2 and D2 antagonist. Cinitapride can be used in functional dyspepsia (FD) and gastroesophageal reflux disease (GERD) research.
  • HY-108242
    Apomorphine hydrochloride
    		Modulator ≥99.0%
    Apomorphine ((-)-Apomorphine) hydrochloride is an orally active agonist of Dopamine receptor. Apomorphine hydrochloride can be used in study Parkinson, biphasic dyskinesias, urinary dysfunction, dystonia, dyspnoea, anismus and belching.
  • HY-W009681
    1-(2-Methoxyphenyl)piperazine hydrochloride
    		Modulator 99.79%
    1-(2-Methoxyphenyl)piperazine hydrochloride is a key agent intermediate of antipsychotics with high affinity to the serotonin receptors and 5-HT, which can be used to synthesize the intestinal worm-repellent agents Piperazine phosphate (HY-B0912C) and Piperazine citrate (HY-17599), as well as Fluphenazine (HY-119980), dihydrochloride, Rifampicin (HY-B0272).
  • HY-125784A
    (R)-Viloxazine hydrochloride
    		Modulator 99.08%
    (R)-Viloxazine hydrochloride is a less active R-isomer of Viloxazine hydrochloride. Viloxazine hydrochloride is an effective antidepressant agent.
  • HY-172982
    CTW0419
    		Modulator
    CTW0419 is a potent 5-HT Receptor positive allosteric modulators (PAMs). CTW0419 is promising for research of neuropsychiatric disorders.
  • HY-124381
    ML10375
    		Modulator
    ML10375 is a compound that modulates 5-HT4 and 5-HT2 receptors, affects gap junction coupling in rat atrial myocytes, and regulates intracellular cAMP concentration and L-type calcium current.
  • HY-172981
    CTW0404
    		Modulator
    CTW0404 is a potent 5-HT Receptor positive allosteric modulators (PAMs). CTW0404 is promising for research of neuropsychiatric disorders.
  • HY-124015
    1,1,1-Trifluoro-10(Z)-nonadecen-2-one
    		Modulator
    1,1,1-Trifluoro-10(Z)-nonadecen-2-one (Compound 1) is an inhibitor of oleamide hydrolase.
  • HY-163728
    DSP-6745
    		Modulator
    DSP-6745 is a potent and orally active 5-HT Receptor inhibitor. DSP-6745 can be used in the study of depressive disorder.
  • HY-W052508R
    Norquetiapine (Standard)
    		Modulator
    Norquetiapine is an antidepressant and neuroprotective agent and is the active metabolic component of Quetiapine (HY-14544). Norquetiapine is also a partial 5-HT1A receptor agonist, and a presynaptic α2, 5-HT2C and 5-HT7 b> Receptor antagonist. Norquetiapine can also selectively inhibit norepinephrine transporter (NET), inhibit norepinephrine reuptake, and has potential inhibitory effects on bipolar depression, major depressive disorder, and generalized anxiety disorder. Norquetiapine demonstrated in vivo activity in forced swimming in mice and learned helplessness tests in rats.
  • HY-16687AR
    Eltoprazine hydrochloride (Standard)
    		Modulator
    Eltoprazine (hydrochloride) (Standard) is the analytical standard of Eltoprazine (hydrochloride). This product is intended for research and analytical applications. Eltoprazine (DU 28853) hydrochloride is a 5-HT1A/5-HT1B receptors agonist and a 5-HT2C receptor antagonist. Eltoprazine hydrochloride shows antiaggressive and anxiogenic effects.
  • HY-B2089R
    Cinitapride (Standard)
    		Modulator
    Cinitapride (Standard) is the analytical standard of Cinitapride. This product is intended for research and analytical applications. Cinitapride is a nonselective 5-HT1 and 5-HT4 receptors agonist and a 5-HT2 and D2 antagonist. Cinitapride can be used in functional dyspepsia (FD) and gastroesophageal reflux disease (GERD) research.
  • HY-32329R
    Setiptiline (Standard)
    		Modulator
    Setiptiline (Standard) is the analytical standard of Setiptiline. This product is intended for research and analytical applications. Setiptiline (Org-8282) is a serotonin receptor antagonist. Setiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). Setiptiline acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes, as well as an H1 receptor inverse agonist/antihistamine.